Bordeaux is a port city on the Garonne River in the Gironde department in southwestern France. The municipality of Bordeaux proper has a population of 243,626. Together with its suburbs and satellite towns, Bordeaux is the centre of the Bordeaux Métropole. With 749,595 inhabitants and 1,178,335 in the metropolitan area, it is the fifth largest in France, after Paris, Marseille, Lyon and Lille, and before Toulouse. It is the capital of the Nouvelle-Aquitaine region, as well as the prefecture of the Gironde department. Its inhabitants are called "Bordelais" or "Bordelaises". The term "Bordelais" may also refer to the city and its surrounding region. Bordeaux is the worlds major wine industry capital. It is home to the worlds main wine fair, Vinexpo, and the wine economy in the metro area takes in 14.5 billion euros each year. Bordeaux wine has been produced in the region since the 8th century. The historic part of the city is on the UNESCO World Heritage List as "an outstanding urban and architectural ensemble" of the 18th century. After Paris, Bordeaux has the highest number of preserved historical buildings of any city in France.